Warning: Spoilers for the Final War arc of My Hero AcademiaIn the battle with Shigaraki, during My Hero Academia's Final War arc, Bakugo pushes himself too hard, causing beads of nitroglycerin to form in his blood, which detonate across his body, causing massive self-inflicted damage. While Bakugo appears to be dead, his actual fate remains unclear, as Edgeshot is desperately trying to revive him when last shown. However, Bakugo's capacity to injure himself in this way was actually hinted at much, much earlier.
